MIR Preclinical Services owns and operates, on site, a 7 Tesla Varian small animal MRI system with a 12 cm imaging bore. The 7 Tesla field strength offers optimal signal to noise ratios and image quality for imaging in vivo tumor models, without the complications that higher fields can present. MIR's imaging staff has optimized animal throughput for a variety of in vivo imaging protocols through innovative animal preparation techniques and implementation of software to facilitate image acquisition and post-processing. MIR optimizes imaging throughput to offer the best value to its clients.

MIR Preclinical Services owns and operates, on site, a high resolution (spatial resolution below 2.0 mm) preclinical PET with Co-Registered CT on the same gantry. This system has the highest sensitivity and largest axial field of view among small animal PET systems, increasing throughput and minimizing costs. The CT system can performn whole body image acquisitions that take less than a minute, to very-high-resolution (43 µm) whole body scans.

Preclinical Siemens PET

MIR Preclinical Services owns and operates, on site, a Xenogen IVIS® Imaging System. This system is physically calibrated and measures actual light photons emitted from the source. This system has a heated base to stabilize kinetic reactions which may create data artifacts. This system also has Xenogen's XFO-12 Fluorescence Option which provides the option of fluorescent imaging in addition to bioluminescent imaging for both in vivo and in vitro applications. The following table shows the fluorescence wavelengths which the system can accommodate.

MIR Preclinical Services owns and operates, on site, a GE RS150 micro-CT scanner. At present, this is a one of a kind instrument with unique hardware that was built to facilitate rapid, high resolution in vivo imaging. This equipment is capable of imaging both dense and soft tissue. MIR utilizes state-of-the-art equipment and is continually seeking new technologies to offer better services to it’s clients.

MIR Preclinical Services utilizes Thoren MaxiMiser® and Biobubble® caging systems for animal housing. The Thoren MaxiMiser® caging systems supply and exhaust air through H.E.P.A. filters for each individual cage. Use of these caging systems minimizes pathogen exposure of the experimental animals on study by providing each individual cage with many complete air changes per hour. All animals housed in Thoren systems, regardless of immune status, are handled and treated in laminar down flow cabinets to minimize risks of environmental exposure. MIR has recently purchased a number of Biobubble® systems, slowly replacing the Thoren MaxiMiser® system in favor of this technology. Biobbubles are isolated enclosed units that shower contents within the bubble with hepafiltered air at 100 air changes per hour.  This system allows isolator cages to sit on racks within the bubble and work to be performed on stainless steel tables, all under the shower of hepafiltered air.  This sterile environment increases efficiency and separates animal colonies, minimizing possible environmental contamination within the facility.

MIR Preclinical Services occupies approximately 20,000 square feet at its Ann Arbor facility that was specifically designed for efficient and flexible function. In addition to the imaging equipment and facilities noted elsewhere, the facility also has newly renovated and specifically designed biology, chemistry, tissue culture, and procedure labs.