XENOGRAFT AND SYNGENEIC TUMOR MODELS AVAILABLE
           
 

Tumor models are continually being added to to MIR's bank and may not have been updated to this list. There are also tumor models in MIR's tumor bank that have been modified to resist certain treatments or have an altered protein expression from wild type. MIR is also willing to develop procure new models for use in client studies. For more information on your particular study needs, please contact us.

Links provided for cell lines are for cell descriptions and availability only and do not necessarily reflect the origin of MIR's cell lines. Also, the ATCC® is not affiliated in any way with MIR Preclinical Services. Information represented here is not an endorsement from the ATCC®.
       
       
 
ALL (Acute Lymphoblastic Leukemia)
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
L1210
No
Available
Mouse lymphoblast
MOLT-4
No
Human lymphoblastic leukemia xenograft
   
       
     
 
AML & CML (Acute & Chronic Myelogenous Leukemia)
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
HL60
No
Human promyelocytic leukemia tumor xenograft
K562
No
Human lymphoblast (CML) tumor xenograft
KG-1
No
Human myeloblast tumor xenograft
OPM-2
No
Human multiple myeloma tumor xenograft
P388
No
Available
Mouse Lymphoma (AML)
THP-1
No
Human monocyte (AML) tumor xenograft
   
       
     
 
Bladder
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
T24
No

Human epithelial tumor xenograft
   
       
     
 
Bone and Connective Tissue
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
EHS
No

Mouse fibroblast
   
       
     
 
Brain
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
9L*
No
Rattus glioma
C6
No

Rattus glioma fibroblast
D54*
No
Human glioblastoma
DBTRG
No
Human glioma multiforme tumor xenograft
SF-295
No
Human glioma tumor xenograft
SF-539
No
Human glioma tumor xenograft
SF767
No
Human Glioma tumor xenograft
SNB-19
No
Human glioblastoma tumor xenograft
U-87
No
Hum. gliobl.-astrocytoma
No
Human glioblastoma tumor xenograft
No
Hum. gliobl.-astrocytoma
   
       
     
 
Breast
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
BT-474
Yes
Human epithelial tumor xenograft
Mammary 13
No
      
Mammary 16
No
      
Mammary 17
No
      
Mammary 25
No
Mammary 212
No
      
Mammary 969
No
MDA-MB-231
Yes
Human epithelial tumor xenograft
MDA-MB-435
N0
Human, spindle shaped
MDA-MB-453
No
Human epithelial tumor xenograft
MDA-MB-468
No
Human epithelial tumor xenograft
MDA-MB-469
No
MCF/7
No
Hum. Mammary Carc. tumor xenograft
MX-1
Yes
Hum. Mammary Carc. tumor xenograft
T-47D
No
Human epithelial tumor xenograft
ZR-75-1
No
Human epithelial tumor xenograft
   
       
     
 
Cervix
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
C-33 A
No

Human epithelial tumor xenograft
   
       
     
 
Colon
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
Colo 205
Yes
Human epithelial tumor xenograft
C26 (Colon26)
No

Mouse
C51
No
Human epithelial tumor xenograft
  
COLON 06
No
COLON 07
No
COLON 08
No
COLON 10
No
COLON 11
No
COLON 12
No
COLON 26
No
COLON 36
No
COLON 38
No
COLON 51
No
      
DLD-1
No
GC3
No
Human carcinoma tumor xenograft
HCT 116
Yes
Human epithelial tumor xenograft
HCT 8
No
Human epithelial tumor xenograft
HT-29
Yes
Human epithelial tumor xenograft
SW620
No
Human epithelial tumor xenograft
   
       
     
 
Head and Neck
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
HONE-T-1
No

H. Nasopharyngeal carc.
   
       
     
 
Lung
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
A549
Yes
Human epithelial (lung) tumor xenograft
H125
No
H. Lung Adenosquamous
H1299
No

Human NSCLC tumor xenograft
H1975
No
Human NSCLC tumor xenograft
H23
No
Human NSCLC tumor xenograft
H249
No
Human NSCLC tumor xenograft
H345
No
Human SCLC tumor xenograft
H460
Yes
Human epithelial (lung) tumor xenograft
H522
No
Human epithelial (lung) tumor xenograft
Lewis Lung
No
      
N-592
No
Human SCLC tumor xenograft
SK-MES-1
No
H. squamous lung carc. tumor xenograft
WI-38
No
Human fibroblast tumor xenograft
   
       
     
 
Ovarian
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
A2780
Yes
Human epithelial tumor xenograft
OVCAR-3
No
Available
Human adenocarcinoma tumor xenograft
OVCAR-4
No
Human adenocarcinoma tumor xenograft
OVCAR-5
No
Human adenocarcinoma tumor xenograft
SK-OV-3
Yes
Human epithelial tumor xenograft
   
       
     
 
Pancreas
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
BxPc-3
Yes
Human epithelial tumor xenograft
Capan-1
No
Human epithelial tumor xenograft
Capan-2
No
Human Polygonal tumor xenograft
Capan-3
No
MIA PaCa-2
Yes
Human epithelial tumor xenograft
pa/III
No
Rat prostate adeno.
Pan 02
No
Mouse adenocarcinoma
Pan 03
No
Mouse adenocarcinoma
Panc-1
No
Human epithelial tumor xenograft
SU.86.86
No
Human epithelial tumor xenograft
   
       
     
 
Prostate
    
 
   
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
No
DU 145
Yes
PC-3*
No
Human epithelial tumor xenograft
   
       
     
 
Renal
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
A498
No

Human epithelial tumor xenograft
   
       
     
 
Skin
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
A375
Yes
Human epithelial tumor xenograft
A431
No
Human epithelial tumor xenograft
B16
No
Mouse
Lox IMVI
No
H. Amelanotic Melanoma tumor xenograft
Malme-3m
No
Human mixed morphology
WM-115
No
Human epithelial tumor xenograft
   
       
     
 
Stomach
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
N87
No
Human epithelial tumor xenograft
   
       
     
 
Uterine
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
DX5
No
Human fibroblast tumor xenograft
MES-SA
No

Human fibroblast tumor xenograft
   
       
     
 
Other
    
       
 
Cell Line
In Continual Passage
Growth Curve
Cell Type/Morphology
ATCC® No.
A4573
No
Human Ewing's sarcoma tumor xenograft
  
DF-1 (AKT, Kras & Raf)
No
Chicken Fibroblast
Ehrlich Ascites
No
Mouse epithelial
EOMA
No
Mouse hemangioendothelioma
H125
No

Human Adenocarcinoma tumor xenograft
HT-1080
Yes
Human fibrosarcoma tumor xenograft
M-MSV/Balb/3T3
No
Moloney murine sarc. Vir.
Saos-2
No
Human osteosarcoma tumor xenograft
   
       
     
  *Special variations of this line exists that contain luciferase or fluorescent reporter constructs    
       
 
ATCC® and the ATCC Catalog Marks are trademarks of American Type Culture Collection.
    
 
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Phone: 734.821.1063 Fax: 734.821.1066
   
updated:  4/7/08